DeepMind has once again taken a significant step in computational biology with the release of AlphaFold 3’s inference codebase, model weights, and an on-demand server. This update brings unprecedented capabilities to the already transformative AlphaFold platform, extending its reach beyond proteins to accurately predict the structure and interactions of almost all of life’s molecules, including nucleic acids, ligands, ions, and modified residues, all in one unified platform. Let’s explore the implications and the technological leap represented by AlphaFold 3. Addressing the Challenges in Biomolecular Structure Prediction The accurate prediction of biomolecular structures is one of the most pressing challenges in